Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 10/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661552 | 0.86 | USP1 (0.48) | USP1S1PR1SMN1; SMN2MAPT | |
| SCHEMBL31661726 | 0.84 | USP1 (0.41) | USP1ALDH1A1S1PR1SMN1; SMN2 | |
| SCHEMBL31661677 | 0.83 | USP1 (0.52) | USP1S1PR1SMN1; SMN2 | |
| SCHEMBL31661653 | 0.83 | USP1 (0.52) | USP1S1PR1SMN1; SMN2 | |
| SCHEMBL31661610 | 0.80 | USP1 (0.47) | USP1S1PR1SMN1; SMN2 | |
| SCHEMBL31661803 | 0.79 | USP1 (0.58) | USP1 | |
| SCHEMBL31661724 | 0.78 | USP1 (0.41) | USP1S1PR1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL31661564 | 0.77 | MEN1 (0.44) | USP1ALDH1A1S1PR1SMN1; SMN2MAPT | |
| SCHEMBL31661670 | 0.77 | USP1 (0.54) | USP1 | |
| SCHEMBL31661695 | 0.77 | S1PR1 (0.46) | USP1S1PR1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |