Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661724 | 0.94 | USP1 (0.41) | USP1POLBS1PR1ADRB2SMN1; SMN2 | |
| SCHEMBL31661695 | 0.93 | S1PR1 (0.46) | USP1POLBS1PR1SMN1; SMN2 | |
| SCHEMBL31661671 | 0.92 | S1PR1 (0.47) | USP1POLBS1PR1SMN1; SMN2 | |
| SCHEMBL31661739 | 0.87 | NPC1 (0.36) | S1PR1HDAC8HDAC6HTTSMN1; SMN2 | |
| SCHEMBL31661787 | 0.84 | USP1 (0.44) | USP1S1PR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31661802 | 0.84 | NPC1 (0.43) | S1PR1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL31661564 | 0.82 | MEN1 (0.44) | USP1POLBS1PR1ALDH1A1HTT | |
| SCHEMBL31661762 | 0.81 | NR1H4 (0.50) | S1PR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31661744 | 0.81 | NR1H4 (0.50) | S1PR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31661659 | 0.79 | LMNA (0.55) | S1PR1ALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | claimed |
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |