SCHEMBL31661670

SCHEMBL31661670

CC(C)c1ccccc1-c1nccc(-c2nc(-c3ccc(-c4nc(C(F)(F)F)cn4C)cc3)no2)n1

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
USP1 O94782 20/20 0.54
WDR48 Q8TAF3 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31661803 0.87 USP1 (0.58) USP1WDR48
SCHEMBL31661653 0.87 USP1 (0.52) USP1WDR48
SCHEMBL31661677 0.87 USP1 (0.52) USP1WDR48
SCHEMBL31661552 0.82 USP1 (0.48) USP1WDR48
SCHEMBL31661610 0.81 USP1 (0.47) USP1WDR48
SCHEMBL31661753 0.81 S1PR1 (0.42) USP1
SCHEMBL30135389 0.78 USP1 (0.60) USP1WDR48
SCHEMBL31661659 0.76 LMNA (0.55)
SCHEMBL31661587 0.76 SMN1; SMN2 (0.56) USP1
SCHEMBL31661630 0.75 PTGS2 (0.46) USP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025151705-A1 NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY VRISE THERAPEUTICS, INC. (US) 2025-07-17 WO claimed
WO-2025151705-A1 NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY VRISE THERAPEUTICS, INC. (US) 2025-07-17 WO disclosed