Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.60 |
| ▸ | HTT | P42858 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.59 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29732825 | 0.82 | KMT2A (0.65) | MEN1KMT2AHTTSMN1; SMN2RAB9A | |
| SCHEMBL28844966 | 0.82 | KMT2A (0.65) | MEN1KMT2AHTTSMN1; SMN2RAB9A | |
| SCHEMBL8888157 | 0.80 | NPC1 (0.75) | MEN1KMT2AHTTSMN1; SMN2LMNA | |
| SCHEMBL30323190 | 0.75 | GRM4 (0.71) | SMN1; SMN2ALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL20524660 | 0.75 | GRM4 (0.71) | SMN1; SMN2ALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL1483884 | 0.75 | RAB9A (0.61) | MEN1KMT2AHTTSMN1; SMN2LMNA | |
| SCHEMBL6669304 | 0.75 | HTT (1.00) | MEN1KMT2AHTTSMN1; SMN2LMNA | |
| SCHEMBL30423494 | 0.74 | MEN1 (0.54) | MEN1KMT2AHTTSMN1; SMN2LMNA | |
| SCHEMBL6667286 | 0.74 | ALDH1A1 (1.00) | MEN1KMT2AHTTSMN1; SMN2LMNA | |
| SCHEMBL28723840 | 0.74 | GPR35 (0.47) | MEN1KMT2AHTTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151311-A1 | NICOTINAMIDE DERIVATIVES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2025-07-17 | — | — | WO | disclosed |