Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2155229 | 0.84 | MAPK8 (0.70) | LMNAHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL14095084 | 0.84 | KDM4E (0.74) | KDM4EHPGDTDP1L3MBTL1KMT2A | |
| SCHEMBL4703988 | 0.84 | KDM4E (1.00) | KDM4ELMNAHPGDTDP1L3MBTL1 | |
| SCHEMBL22983344 | 0.77 | TP53 (0.77) | KDM4ELMNAHPGDL3MBTL1KMT2A | |
| SCHEMBL6542858 | 0.76 | KDM4E (0.60) | KDM4ELMNAHPGDKMT2AMEN1 | |
| SCHEMBL17859660 | 0.76 | KDM4E (0.72) | KDM4EHPGDTDP1L3MBTL1KMT2A | |
| SCHEMBL204732 | 0.74 | KDM4E (0.65) | KDM4ELMNAHPGDL3MBTL1KMT2A | |
| SCHEMBL14880158 | 0.74 | RAB9A (0.70) | LMNATDP1KMT2AALDH1A1RAB9A | |
| SCHEMBL7398166 | 0.74 | MAPK10 (0.69) | KDM4EHPGDTDP1L3MBTL1KMT2A | |
| SCHEMBL267882 | 0.74 | KDM4E (0.69) | KDM4EHPGDTDP1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151311-A1 | NICOTINAMIDE DERIVATIVES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2025-07-17 | — | — | WO | disclosed |