SCHEMBL2155229

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31661836	0.84	KDM4E (0.71)	KMT2AMEN1MAPTALDH1A1POLB
	SCHEMBL28679510	0.76	MAPK8 (0.63)	MAPK8KMT2AMEN1MAPTALDH1A1
	SCHEMBL7287487	0.76	SIRT2 (0.76)	MAPTALDH1A1SIRT2LMNAHIF1A
	SCHEMBL28665656	0.75	MAPK8 (0.58)	MAPK8MAPK10PTK2
	SCHEMBL571346	0.75	SIRT2 (0.60)	MAPTALDH1A1SIRT2NPC1RAB9A
	SCHEMBL7565219	0.75	NAMPT (0.66)	MAPK8KMT2AMEN1ALDH1A1LMNA
	SCHEMBL16264348	0.75	MAPK8 (0.60)	MAPK8KMT2AMEN1MAPTALDH1A1
	SCHEMBL3178619	0.74	NPC1 (0.72)	KMT2AMEN1NPC1RAB9ALMNA
	SCHEMBL13789353	0.74	MAPK8 (0.73)	MAPK8KMT2AMEN1MAPTALDH1A1
	SCHEMBL24489078	0.73	MAPK10 (1.00)	MAPK8KMT2AMEN1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.