SCHEMBL31661869

SCHEMBL31661869

N#Cc1ccc(-c2ccsc2C(N)=O)cn1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.53
CTSA P10619 1/20 0.42
MYC P01106 1/20 0.40
PTPN1 P18031 1/20 0.39
GRM2 Q14416 2/20 0.38
ALDH1A1 P00352 3/20 0.37
NPSR1 Q6W5P4 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CHEK2 O96017 2/20 0.37
PDE10A Q9Y233 1/20 0.36
POLQ O75417 1/20 0.36
VHL P40337 1/20 0.36
GPR119 Q8TDV5 1/20 0.35
PARP1 P09874 1/20 0.35
PIK3CA P42336 2/20 0.35
KDM4E B2RXH2 1/20 0.35
POLB P06746 1/20 0.35
EGLN2 Q96KS0 1/20 0.35
CHEK1 O14757 1/20 0.34
PTGS1 P23219 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31661820 0.79 BCAT2 (0.58) BCAT2ALDH1A1CHEK2KDM4EPOLB
SCHEMBL31661900 0.78 BCAT2 (0.57) BCAT2ALDH1A1CHEK2KDM4EPOLB
SCHEMBL31661924 0.73 BCAT2 (0.51) BCAT2CHEK2CHEK1PTGS1
SCHEMBL31661908 0.71 BCAT2 (0.53) BCAT2ALDH1A1CHEK2KDM4ECHEK1
SCHEMBL28130086 0.71 BCAT2 (0.65) BCAT2ALDH1A1NPSR1L3MBTL1CHEK2
SCHEMBL2231308 0.70 BCAT2 (0.69) BCAT2GRM2ALDH1A1L3MBTL1KDM4E
SCHEMBL6667283 0.70 BCAT2 (0.69) BCAT2ALDH1A1CHEK2PTGS1
SCHEMBL27353967 0.70 BCAT2 (0.69) BCAT2PTGS1
SCHEMBL6669302 0.70 BCAT2 (0.68) BCAT2ALDH1A1CHEK2
SCHEMBL4445671 0.70 BCAT2 (1.00) BCAT2ALDH1A1L3MBTL1PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025151311-A1 NICOTINAMIDE DERIVATIVES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-07-17 WO disclosed