Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 3/20 | 0.34 |
| ▸ | SELE | P16581 | 3/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.32 |
| ▸ | JAK3 | P52333 | 5/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.31 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662205 | 0.82 | CYP11B2 (0.34) | ICAM1SELECYP11B2BMPR1BBMPR1A | |
| SCHEMBL31661992 | 0.78 | PDE4D (0.34) | PDE4D | |
| SCHEMBL31662082 | 0.78 | TBXAS1 (0.34) | ICAM1SELETBXAS1HRH3PARP10 | |
| SCHEMBL31661983 | 0.78 | CNR2 (0.32) | HRH3JAK3OPRK1OPRM1OPRD1 | |
| SCHEMBL31662171 | 0.78 | TTK (0.36) | JAK3 | |
| SCHEMBL31662332 | 0.78 | MIF (0.34) | CYP11B2 | |
| SCHEMBL31662072 | 0.77 | SCN9A (0.39) | HRH3PDE4D | |
| SCHEMBL31662059 | 0.76 | PDE4D (0.35) | PARP10CYP11B2PDE4D | |
| SCHEMBL17888615 | 0.76 | PDE4D (0.38) | HRH3PARP10PARP15PARP2PDE4D | |
| SCHEMBL17888598 | 0.76 | PARP10 (0.38) | HRH3PARP10PARP15PARP2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |