Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | CD38 | P28907 | 3/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 7/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662413 | 0.89 | CD38 (0.39) | PDE4DCD38NAMPT | |
| SCHEMBL31662148 | 0.83 | BTK (0.37) | TBK1CYP11B1CYP11B2 | |
| SCHEMBL31662072 | 0.81 | SCN9A (0.39) | PDE4DCD38CHEK2 | |
| SCHEMBL17899127 | 0.77 | CHEK2 (0.38) | PDE4DCHEK2PARP10 | |
| SCHEMBL17888615 | 0.76 | PDE4D (0.38) | PDE4DCHEK2PARP10TBK1 | |
| SCHEMBL17888598 | 0.76 | PARP10 (0.38) | PDE4DCHEK2PARP10 | |
| SCHEMBL31661893 | 0.76 | SCN9A (0.38) | PDE4DCD38 | |
| SCHEMBL31662085 | 0.76 | SCN9A (0.38) | PDE4DCD38 | |
| SCHEMBL31661916 | 0.76 | ICAM1 (0.34) | PDE4DPARP10CYP11B2 | |
| SCHEMBL17899375 | 0.76 | CHEK2 (0.39) | PDE4DCHEK2PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |