Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 8/20 | 0.40 |
| ▸ | HRH1 | P35367 | 8/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662012 | 0.85 | PRKAB2 (0.40) | HRH2HRH1HRH3GAAPKM | |
| SCHEMBL31662252 | 0.82 | TLR8 (0.38) | GAAPKMLMNAMAPK1HTT | |
| SCHEMBL31662250 | 0.81 | HRH3 (0.46) | CYP4F2CYP4A11DRD3HRH2HRH1 | |
| SCHEMBL31661851 | 0.78 | TLR8 (0.32) | HRH3LMNAHTT | |
| SCHEMBL31662163 | 0.75 | SMN1; SMN2 (0.34) | GAAPKMLMNAMAPK1HTT | |
| SCHEMBL31661961 | 0.72 | PRKAB2 (0.38) | HRH2HRH1HRH3MAPK1 | |
| SCHEMBL31662137 | 0.69 | HRH2 (0.42) | CYP4F2CYP4A11DRD3HRH2HRH1 | |
| SCHEMBL31662074 | 0.68 | CYP2D6 (0.36) | — | |
| SCHEMBL10200150 | 0.67 | DRD3 (0.68) | CYP4F2CYP4A11DRD3HRH2HRH1 | |
| SCHEMBL31662204 | 0.66 | CYP2D6 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |