Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 5/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | AGER | Q15109 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661943 | 0.92 | L3MBTL1 (0.35) | CYP2D6CYP2C9CYP3A4GPR119 | |
| SCHEMBL31662204 | 0.90 | CYP2D6 (0.36) | CYP2D6CYP2C9CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL31661987 | 0.89 | CYP3A4 (0.33) | CYP2D6CYP2C9CYP3A4GPR119 | |
| SCHEMBL31661982 | 0.87 | GPR119 (0.34) | CYP2D6CYP2C9CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL31662621 | 0.87 | GPR119 (0.33) | GPR119QPCTL | |
| SCHEMBL31662494 | 0.83 | CA12 (0.36) | CYP2D6CYP2C9CYP3A4GPR119 | |
| SCHEMBL31661926 | 0.82 | TTK (0.32) | CYP2D6CYP2C9CYP3A4 | |
| SCHEMBL31662252 | 0.82 | TLR8 (0.38) | — | |
| SCHEMBL31661961 | 0.81 | PRKAB2 (0.38) | — | |
| SCHEMBL31662193 | 0.78 | TBXAS1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |