Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.46 |
| ▸ | HRH2 | P25021 | 4/20 | 0.46 |
| ▸ | HRH1 | P35367 | 4/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662459 | 0.82 | TBXAS1 (0.40) | HRH3 | |
| SCHEMBL31661950 | 0.81 | CYP4F2 (0.42) | HRH3HRH2HRH1DRD3CYP4F2 | |
| SCHEMBL31661860 | 0.80 | POLB (0.42) | HRH3KDM4E | |
| SCHEMBL31661965 | 0.80 | SCN9A (0.39) | HRH3 | |
| SCHEMBL31662147 | 0.80 | CYP11B2 (0.39) | HRH3 | |
| SCHEMBL31662117 | 0.79 | GRM2 (0.35) | HRH3KDM4EEPHX2 | |
| SCHEMBL31662136 | 0.79 | HRH3 (0.42) | HRH3HRH2HRH1 | |
| SCHEMBL31662149 | 0.78 | PRKAB2 (0.44) | HRH3KDM4E | |
| SCHEMBL31662185 | 0.77 | HRH3 (0.37) | HRH3HRH2HRH1 | |
| SCHEMBL31662424 | 0.75 | PARP10 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |