Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 7/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | ATF4 | P18848 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CD38 | P28907 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662085 | 1.00 | SCN9A (0.38) | SCN9APDE4DPDE4APDE4BPDE4C | |
| SCHEMBL31662072 | 0.95 | SCN9A (0.39) | SCN9APDE4DHRH3CD38 | |
| SCHEMBL31662015 | 0.90 | SCN9A (0.36) | SCN9APDE4DPDE4APDE4BPDE4C | |
| SCHEMBL31661963 | 0.90 | SCN9A (0.36) | SCN9APDE4DPDE4APDE4BPDE4C | |
| SCHEMBL31662522 | 0.90 | SCN9A (0.36) | SCN9APDE4DPDE4APDE4BPDE4C | |
| SCHEMBL31662035 | 0.87 | SCN9A (0.39) | SCN9AHRH3CD38 | |
| SCHEMBL31662578 | 0.87 | CD38 (0.37) | SCN9APDE4DHRH3HPGDSGCK | |
| SCHEMBL31662235 | 0.86 | CD38 (0.39) | SCN9APDE4DHRH3HPGDSGCK | |
| SCHEMBL31661975 | 0.86 | CHEK2 (0.41) | SCN9AHRH3CD38 | |
| SCHEMBL31662620 | 0.85 | CD38 (0.40) | PDE4DHRH3HPGDSCD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |