Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.36 |
| ▸ | SYK | P43405 | 3/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.32 |
| ▸ | CD38 | P28907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662113 | 0.93 | SCN9A (0.39) | SCN9ASYKROCK2HTR3ADRD4 | |
| SCHEMBL31661960 | 0.91 | SCN1A (0.37) | SCN9ASYKROCK2DRD4TMEM97 | |
| SCHEMBL31662165 | 0.89 | IRAK4 (0.37) | SCN9ASYKROCK2RETJAK2 | |
| SCHEMBL31661875 | 0.89 | SCN9A (0.40) | SCN9ASYKROCK2HAO1IRAK4 | |
| SCHEMBL31661986 | 0.87 | CHEK2 (0.40) | SCN9ADRD4TMEM97SIGMAR1JAK2 | |
| SCHEMBL31662354 | 0.86 | SCN9A (0.38) | SCN9ASYKROCK2JAK2JAK1 | |
| SCHEMBL31662101 | 0.86 | MAPT (0.38) | SCN9ADRD4TMEM97SIGMAR1 | |
| SCHEMBL31662071 | 0.86 | SCN9A (0.38) | SCN9ASYKROCK2JAK2JAK1 | |
| SCHEMBL31662133 | 0.86 | OPRK1 (0.38) | SCN9ASYKROCK2HTR3A | |
| SCHEMBL31662124 | 0.85 | SCN9A (0.36) | SCN9ASYKROCK2HTR3ARET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |