Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | NEK2 | P51955 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | JAK3 | P52333 | 2/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662113 | 0.94 | SCN9A (0.39) | SCN9ADRD4SIGMAR1TMEM97ROCK2 | |
| SCHEMBL31661986 | 0.92 | CHEK2 (0.40) | SCN9ADRD4SIGMAR1TMEM97JAK2 | |
| SCHEMBL31662101 | 0.91 | MAPT (0.38) | SCN9ADRD4SIGMAR1TMEM97RAB9A | |
| SCHEMBL31661999 | 0.91 | SCN9A (0.36) | SCN9ADRD4SIGMAR1TMEM97ROCK2 | |
| SCHEMBL31662291 | 0.91 | NTRK1 (0.38) | SCN9ADRD4SIGMAR1TMEM97RAB9A | |
| SCHEMBL31662165 | 0.90 | IRAK4 (0.37) | SCN9AROCK2JAK2JAK1JAK3 | |
| SCHEMBL31661875 | 0.90 | SCN9A (0.40) | SCN9AROCK2CHEK2SYK | |
| SCHEMBL31661890 | 0.89 | NTRK1 (0.37) | SCN9AJAK2JAK1JAK3MAPT | |
| SCHEMBL31662354 | 0.88 | SCN9A (0.38) | SCN9AROCK2JAK2JAK1JAK3 | |
| SCHEMBL31662133 | 0.88 | OPRK1 (0.38) | SCN9AROCK2SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |