Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 8/20 | 0.38 |
| ▸ | IKBKB | O14920 | 5/20 | 0.35 |
| ▸ | HTR3A | P46098 | 3/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662190 | 0.89 | SMN1; SMN2 (0.42) | SCN9AHTR3ACHEK2 | |
| SCHEMBL31662096 | 0.86 | PRKAB2 (0.42) | SCN9AHTR3ACHEK2HRH3 | |
| SCHEMBL31662002 | 0.86 | SCN9A (0.37) | SCN9AHTR3ACHEK2HRH3MCL1 | |
| SCHEMBL31661967 | 0.84 | PRKAB2 (0.41) | SCN9AIKBKBHTR3ACHEK2HRH3 | |
| SCHEMBL31662167 | 0.84 | SCN9A (0.38) | SCN9AHTR3ACHEK2 | |
| SCHEMBL31662062 | 0.84 | CCNC (0.47) | SCN9A | |
| SCHEMBL31662018 | 0.83 | SCN9A (0.39) | SCN9AHTR3ACHEK2 | |
| SCHEMBL31662377 | 0.82 | SCN9A (0.43) | SCN9ACHEK2HRH3MCL1 | |
| SCHEMBL31662175 | 0.81 | HRH3 (0.47) | HRH3 | |
| SCHEMBL31662417 | 0.80 | SCN9A (0.41) | SCN9AMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |