Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 9/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662527 | 0.88 | MAPT (0.41) | SCN9A | |
| SCHEMBL31662417 | 0.88 | SCN9A (0.41) | SCN9AMCL1TBXAS1HPGDSPARP10 | |
| SCHEMBL31662603 | 0.88 | SCN9A (0.38) | SCN9A | |
| SCHEMBL31662222 | 0.87 | TBXAS1 (0.43) | SCN9ATBXAS1HPGDS | |
| SCHEMBL31662175 | 0.85 | HRH3 (0.47) | HRH3 | |
| SCHEMBL31662580 | 0.84 | PARP10 (0.46) | SCN9AHPGDSPARP10CHEK2F2 | |
| SCHEMBL31661931 | 0.84 | SCN9A (0.38) | SCN9ATBXAS1PARP10CHEK2 | |
| SCHEMBL31662144 | 0.83 | PARP15 (0.51) | SCN9APARP10CHEK2 | |
| SCHEMBL31662190 | 0.83 | SMN1; SMN2 (0.42) | SCN9ACHEK2 | |
| SCHEMBL31662035 | 0.83 | SCN9A (0.39) | SCN9AHRH3CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |