Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.40 |
| ▸ | EGFR | P00533 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662190 | 0.96 | SMN1; SMN2 (0.42) | CCNCCDK8POLBPDK2EGFR | |
| SCHEMBL31662018 | 0.86 | SCN9A (0.39) | CCNCCDK8SCN9A | |
| SCHEMBL31662157 | 0.85 | CYP11B2 (0.41) | PDK2SCN9A | |
| SCHEMBL31662052 | 0.84 | SCN9A (0.38) | SCN9A | |
| SCHEMBL31662096 | 0.83 | PRKAB2 (0.42) | PDK2SCN9AKMT2ALMNA | |
| SCHEMBL31662002 | 0.83 | SCN9A (0.37) | SMN1; SMN2SCN9AMEN1KMT2A | |
| SCHEMBL31662377 | 0.82 | SCN9A (0.43) | SCN9A | |
| SCHEMBL31662222 | 0.81 | TBXAS1 (0.43) | SCN9AMEN1KMT2ALMNA | |
| SCHEMBL31662417 | 0.81 | SCN9A (0.41) | SCN9A | |
| SCHEMBL31662167 | 0.81 | SCN9A (0.38) | PDK2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |