Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CD38 | P28907 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662457 | 0.84 | CD38 (0.34) | ATMLTA4HALDH1A1SMN1; SMN2CD38 | |
| SCHEMBL31662230 | 0.84 | CD38 (0.34) | ATMLTA4HALDH1A1CD38MAPK14 | |
| SCHEMBL31662578 | 0.83 | CD38 (0.37) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL31662072 | 0.82 | SCN9A (0.39) | CD38MAPK14 | |
| SCHEMBL31662620 | 0.81 | CD38 (0.40) | L3MBTL1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL31662289 | 0.81 | CD38 (0.32) | CD38MAPK14 | |
| SCHEMBL31662235 | 0.81 | CD38 (0.39) | CD38MAPK14 | |
| SCHEMBL31662006 | 0.79 | GCK (0.43) | MEN1KMT2AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL31662202 | 0.79 | GSK3B (0.36) | ATMLTA4HCD38MAPK14 | |
| SCHEMBL31662008 | 0.78 | CD38 (0.46) | CD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |