Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662072 | 0.92 | SCN9A (0.39) | CD38HRH3PDE4DMAPK14SCN9A | |
| SCHEMBL31662620 | 0.91 | CD38 (0.40) | CD38HRH3KDM4EALDH1A1PDE4D | |
| SCHEMBL31662235 | 0.90 | CD38 (0.39) | CD38HRH3PDE4DMAPK14SCN9A | |
| SCHEMBL31662006 | 0.89 | GCK (0.43) | HRH3ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31661893 | 0.87 | SCN9A (0.38) | CD38HRH3PDE4DSCN9AGCK | |
| SCHEMBL31662085 | 0.87 | SCN9A (0.38) | CD38HRH3PDE4DSCN9AGCK | |
| SCHEMBL31662230 | 0.85 | CD38 (0.34) | CD38HRH3ALDH1A1MAPK14 | |
| SCHEMBL31662457 | 0.85 | CD38 (0.34) | CD38HRH3ALDH1A1MAPK14SMN1; SMN2 | |
| SCHEMBL31662385 | 0.84 | CHEK2 (0.41) | KDM4EALDH1A1PDE4DMEN1KMT2A | |
| SCHEMBL31662428 | 0.84 | DHODH (0.37) | CD38HRH3KDM4EHAO1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |