Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662230 | 0.88 | CD38 (0.34) | CD38MAPK14ADORA2AHTR6LRRK2 | |
| SCHEMBL31662072 | 0.86 | SCN9A (0.39) | CD38MAPK14HRH3 | |
| SCHEMBL31662578 | 0.85 | CD38 (0.37) | CD38MAPK14SMN1; SMN2HRH3ALDH1A1 | |
| SCHEMBL31662235 | 0.85 | CD38 (0.39) | CD38MAPK14KCNH2HRH3 | |
| SCHEMBL31662231 | 0.84 | ATM (0.38) | CD38MAPK14SMN1; SMN2LTA4HATM | |
| SCHEMBL31662620 | 0.83 | CD38 (0.40) | CD38MAPK14SMN1; SMN2LRRK2HRH3 | |
| SCHEMBL31662202 | 0.83 | GSK3B (0.36) | CD38MAPK14HTR6LRRK2LTA4H | |
| SCHEMBL31662289 | 0.83 | CD38 (0.32) | CD38MAPK14HTR6LRRK2 | |
| SCHEMBL31661923 | 0.82 | TTK (0.38) | CD38HTR6LRRK2 | |
| SCHEMBL31662008 | 0.82 | CD38 (0.46) | CD38HRH3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |