Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662457 | 0.88 | CD38 (0.34) | CD38MAPK14HTR6LRRK2LTA4H | |
| SCHEMBL31662578 | 0.85 | CD38 (0.37) | CD38MAPK14HRH3ALDH1A1 | |
| SCHEMBL31662072 | 0.84 | SCN9A (0.39) | CD38MAPK14HRH3 | |
| SCHEMBL31662231 | 0.84 | ATM (0.38) | CD38MAPK14LTA4HATMMAPK1 | |
| SCHEMBL31662620 | 0.83 | CD38 (0.40) | CD38MAPK14LRRK2HRH3ALDH1A1 | |
| SCHEMBL31662202 | 0.83 | GSK3B (0.36) | CD38MAPK14HTR6LRRK2LTA4H | |
| SCHEMBL31662235 | 0.83 | CD38 (0.39) | CD38MAPK14KCNH2HRH3 | |
| SCHEMBL31662289 | 0.83 | CD38 (0.32) | CD38MAPK14HTR6LRRK2 | |
| SCHEMBL31661923 | 0.82 | TTK (0.38) | CD38HTR6LRRK2 | |
| SCHEMBL31662008 | 0.82 | CD38 (0.46) | CD38HRH3CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |