Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 4/20 | 0.34 |
| ▸ | SYK | P43405 | 4/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.31 |
| ▸ | CD38 | P28907 | 1/20 | 0.31 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 2/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662152 | 0.90 | SCN9A (0.35) | SCN9ASYKROCK2TRPC6OPRM1 | |
| SCHEMBL31662133 | 0.89 | OPRK1 (0.38) | SCN9ASYKROCK2OPRM1OPRK1 | |
| SCHEMBL31661890 | 0.87 | NTRK1 (0.37) | SCN9ASYKJAK2NTRK1KDM1A | |
| SCHEMBL31661904 | 0.87 | CCNC (0.34) | SCN9ASYKROCK2PDE1CJAK2 | |
| SCHEMBL31662113 | 0.86 | SCN9A (0.39) | SCN9ASYKROCK2CD38 | |
| SCHEMBL31662071 | 0.84 | SCN9A (0.38) | SCN9ASYKROCK2PDE1CJAK2 | |
| SCHEMBL31662124 | 0.84 | SCN9A (0.36) | SCN9ASYKROCK2 | |
| SCHEMBL31661960 | 0.83 | SCN1A (0.37) | SCN9ASYKROCK2JAK2JAK1 | |
| SCHEMBL31661875 | 0.82 | SCN9A (0.40) | SCN9ASYKROCK2KDM1A | |
| SCHEMBL31662354 | 0.82 | SCN9A (0.38) | SCN9ASYKROCK2PDE1CJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |