Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662291 | 0.94 | NTRK1 (0.38) | NTRK1KCNH2NTRK2NTRK3KDM1A | |
| SCHEMBL31661904 | 0.92 | CCNC (0.34) | JAK2JAK1SYKJAK3SCN9A | |
| SCHEMBL31661986 | 0.90 | CHEK2 (0.40) | NTRK1KCNH2NTRK2JAK2JAK3 | |
| SCHEMBL31662101 | 0.89 | MAPT (0.38) | NTRK1KCNH2NTRK2MAPTKMT2A | |
| SCHEMBL31661960 | 0.89 | SCN1A (0.37) | MAPTJAK2JAK1SYKJAK3 | |
| SCHEMBL31662113 | 0.89 | SCN9A (0.39) | SYKSCN9A | |
| SCHEMBL31662232 | 0.87 | SCN9A (0.34) | NTRK1JAK2JAK1SYKJAK3 | |
| SCHEMBL31662561 | 0.86 | CHEK2 (0.44) | — | |
| SCHEMBL31661991 | 0.86 | DRD2 (0.41) | POLB | |
| SCHEMBL31662165 | 0.85 | IRAK4 (0.37) | NTRK1JAK2JAK1SYKJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |