Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | MST1R | Q04912 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | CAMK4 | Q16566 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662208 | 0.88 | HPGD (0.42) | SCN9APDE3BPDE3AP2RY12NTRK1 | |
| SCHEMBL31662493 | 0.88 | L3MBTL1 (0.41) | SCN9AARPDE3BPDE3AP2RY12 | |
| SCHEMBL31661937 | 0.88 | PDE3B (0.39) | SCN9APDE3BPDE3AP2RY12ROCK2 | |
| SCHEMBL31662130 | 0.86 | PARP1 (0.40) | SCN9APDE3BPDE3AP2RY12ROCK2 | |
| SCHEMBL31662140 | 0.86 | GAA (0.46) | ARPDE3BPDE3AP2RY12NTRK1 | |
| SCHEMBL31662211 | 0.85 | NTRK1 (0.40) | NTRK1PARP10 | |
| SCHEMBL31662000 | 0.84 | DRD4 (0.34) | SCN9AARROCK2PLK4NTRK1 | |
| SCHEMBL31662381 | 0.82 | SCN9A (0.37) | SCN9AARPPARGFFAR1PPARD | |
| SCHEMBL31662520 | 0.82 | AR (0.40) | SCN9AARROCK2MAPK14PLK4 | |
| SCHEMBL31662453 | 0.80 | MKNK1 (0.39) | SCN9AARROCK2MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |