Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1C | Q14123 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.43 |
| ▸ | MCHR2 | Q969V1 | 2/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662388 | 0.91 | SRD5A2 (0.47) | PDE1CMAPK14MEN1KMT2AMCHR1 | |
| SCHEMBL31662602 | 0.89 | PARP10 (0.46) | PDE1CMAPK14MEN1KMT2AMCHR1 | |
| SCHEMBL31662194 | 0.86 | SCN9A (0.43) | PDE1CSMN1; SMN2CYP2C19NOTUM | |
| SCHEMBL31662415 | 0.83 | SCN9A (0.46) | PDE1CKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31662262 | 0.81 | LMNA (0.46) | MAPK14MEN1KMT2ANPC1RAB9A | |
| SCHEMBL31662426 | 0.80 | CYP4A11 (0.44) | PDE1CSMN1; SMN2NOTUM | |
| SCHEMBL31662169 | 0.80 | SCN9A (0.44) | PDE1CSMN1; SMN2NOTUM | |
| SCHEMBL31662635 | 0.77 | SCN9A (0.48) | PDE1CNOTUM | |
| SCHEMBL31662421 | 0.74 | MCL1 (0.44) | MEN1KMT2ANOTUM | |
| SCHEMBL31662483 | 0.74 | SYK (0.41) | PDE1CNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |