Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 3/20 | 0.38 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662194 | 0.87 | SCN9A (0.43) | SCN9AUSP7HAO1HIPK4NOTUM | |
| SCHEMBL31662421 | 0.86 | MCL1 (0.44) | SYKSCN9AHAO1ARNOTUM | |
| SCHEMBL31662453 | 0.86 | MKNK1 (0.39) | SYKSCN9AHAO1ARNOTUM | |
| SCHEMBL31662602 | 0.86 | PARP10 (0.46) | SYKPARP10ARPDE1C | |
| SCHEMBL31662511 | 0.85 | SYK (0.38) | SYKSCN9AHAO1ARHIPK4 | |
| SCHEMBL31662493 | 0.84 | L3MBTL1 (0.41) | SYKSCN9AHAO1ARNOTUM | |
| SCHEMBL31662521 | 0.84 | SCN9A (0.41) | SYKSCN9AHAO1ARHIPK4 | |
| SCHEMBL31662520 | 0.84 | AR (0.40) | SYKSCN9AAR | |
| SCHEMBL31662391 | 0.81 | GPR119 (0.37) | SYKSCN9APARP10IRAK4PDE1C | |
| SCHEMBL30987739 | 0.80 | KDM4E (0.44) | SYKARIRAK4NOTUMPDE1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |