Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662519 | 0.85 | CA12 (0.41) | LMNAHPGDMEN1KMT2ANPSR1 | |
| SCHEMBL31662527 | 0.84 | MAPT (0.41) | LMNAHPGDMEN1KMT2ACYP2C19 | |
| SCHEMBL31662315 | 0.84 | MAPT (0.41) | LMNAHPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31662290 | 0.82 | USP2 (0.39) | LMNAKMT2ANPSR1SMN1; SMN2NPC1 | |
| SCHEMBL31662553 | 0.81 | KIT (0.40) | MEN1KMT2APOLBCYP2C19NPSR1 | |
| SCHEMBL31662283 | 0.81 | PDE1C (0.43) | MEN1KMT2APOLBCYP2C19NPSR1 | |
| SCHEMBL31662488 | 0.80 | LMNA (0.37) | LMNASMN1; SMN2MRGPRX4MAPTUSP2 | |
| SCHEMBL31662347 | 0.76 | LMNA (0.38) | LMNAHPGDMEN1KMT2APOLB | |
| SCHEMBL31662404 | 0.76 | SCN9A (0.40) | LMNAHPGDMEN1KMT2AMAOB | |
| SCHEMBL31662294 | 0.76 | HAO1 (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |