Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662197 | 0.79 | MCHR1 (0.47) | LMNASMN1; SMN2PKMGRM2 | |
| SCHEMBL14889068 | 0.73 | MAPT (0.39) | ESR1ESR2KMT2AMAPTKDM4E | |
| SCHEMBL31662406 | 0.69 | SCN9A (0.43) | DRD2 | |
| SCHEMBL19244972 | 0.64 | ALDH1A1 (0.52) | ESR1ESR2KMT2AMAPTKDM4E | |
| SCHEMBL12362740 | 0.64 | TDP1 (0.41) | ESR1ESR2KMT2AMAPTKDM4E | |
| SCHEMBL1728613 | 0.61 | HRH3 (0.46) | ALDH1A1GRM2 | |
| SCHEMBL25392115 | 0.61 | EPHX2 (0.39) | KMT2AMAPTALDH1A1LMNATDP1 | |
| SCHEMBL9038758 | 0.61 | MAPT (0.48) | KMT2AMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL31662379 | 0.61 | KMT2A (0.35) | ESR1ESR2KMT2AMAPTKDM4E | |
| SCHEMBL22511492 | 0.60 | BRD4 (0.38) | KMT2AKDM4EALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |