Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12362740 | 0.72 | TDP1 (0.41) | KMT2APKMNPSR1TDP1HSP90AA1 | |
| SCHEMBL19244972 | 0.68 | ALDH1A1 (0.52) | KMT2APKMNPSR1TDP1HSP90AA1 | |
| SCHEMBL14889068 | 0.68 | MAPT (0.39) | KMT2APKMNPSR1TDP1HSP90AA1 | |
| SCHEMBL9038758 | 0.68 | MAPT (0.48) | KMT2APKMNPSR1TDP1MAPT | |
| SCHEMBL31339608 | 0.67 | KDM4E (0.37) | KMT2AMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL1728613 | 0.62 | HRH3 (0.46) | ALDH1A1 | |
| SCHEMBL5256770 | 0.61 | RAB9A (0.53) | KMT2APKMNPSR1TDP1HSP90AA1 | |
| SCHEMBL31662370 | 0.61 | ESR1 (0.32) | KMT2APKMNPSR1TDP1HSP90AA1 | |
| Bromide SCHEMBL6763251 | 0.60 | LTA4H (0.56) | KMT2AMGLLMEN1ESR1ESR2 | |
| SCHEMBL142916 | 0.60 | MEN1 (0.54) | KMT2APKMNPSR1TDP1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |