Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.39 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 4/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662511 | 0.90 | SYK (0.38) | SCN9ASYKHAO1NOTUMAR | |
| SCHEMBL31662493 | 0.89 | L3MBTL1 (0.41) | SCN9ASYKHAO1NOTUMLTA4H | |
| SCHEMBL31662421 | 0.87 | MCL1 (0.44) | SCN9ASYKHAO1NOTUMAR | |
| SCHEMBL31662483 | 0.86 | SYK (0.41) | SCN9ASYKHAO1NOTUMAR | |
| SCHEMBL31662113 | 0.86 | SCN9A (0.39) | SCN9ASYKHAO1ROCK2CACNA1H | |
| SCHEMBL31662092 | 0.86 | SYK (0.37) | SCN9ASYKHAO1NOTUMAR | |
| SCHEMBL31662153 | 0.85 | IKBKB (0.46) | AURKB | |
| SCHEMBL31662189 | 0.85 | SCN9A (0.37) | SCN9ASYKHAO1CACNA1H | |
| SCHEMBL31662602 | 0.84 | PARP10 (0.46) | SYKARMCL1 | |
| SCHEMBL31662521 | 0.82 | SCN9A (0.41) | SCN9ASYKHAO1NOTUMAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |