Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662453 | 0.86 | MKNK1 (0.39) | SYKROCK2HAO1SCN9AAR | |
| SCHEMBL31662511 | 0.85 | SYK (0.38) | SYKHAO1SCN9AARMCL1 | |
| SCHEMBL31662493 | 0.84 | L3MBTL1 (0.41) | SYKHAO1SCN9AARMCL1 | |
| SCHEMBL31662421 | 0.81 | MCL1 (0.44) | SYKHAO1SCN9AARMCL1 | |
| SCHEMBL31662557 | 0.81 | SYK (0.41) | SYKROCK2HAO1MCL1NOTUM | |
| SCHEMBL31662505 | 0.81 | CA12 (0.48) | ROCK2SCN9ACACNA1H | |
| SCHEMBL31662483 | 0.81 | SYK (0.41) | SYKHAO1SCN9AARNOTUM | |
| SCHEMBL31662113 | 0.80 | SCN9A (0.39) | SYKROCK2HAO1SCN9ACACNA1H | |
| SCHEMBL31662354 | 0.80 | SCN9A (0.38) | SYKROCK2HAO1SCN9APDE1C | |
| SCHEMBL31662602 | 0.79 | PARP10 (0.46) | SYKARMCL1MCHR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |