SCHEMBL31662758 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	AKT1	P31749	10/20	0.42

▸	AKT2	P31751	10/20	0.42

▸	DRD2	P14416	3/20	0.40

▸	DRD4	P21917	3/20	0.40

▸	DRD3	P35462	2/20	0.40

▸	WNT1	P04628	1/20	0.36

▸	GRM4	Q14833	1/20	0.36

▸	TLR9	Q9NR96	2/20	0.35

▸	TLR8	Q9NR97	2/20	0.35

▸	TLR7	Q9NYK1	2/20	0.35

▸	PIM1	P11309	1/20	0.35

▸	OPRM1	P35372	1/20	0.34

▸	OPRK1	P41145	1/20	0.34

▸	OPRL1	P41146	1/20	0.34

▸	CTSS	P25774	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31663134	0.76	DRD2 (0.47)	AKT1AKT2DRD2DRD4DRD3
SCHEMBL31663092	0.76	DRD2 (0.47)	AKT1AKT2DRD2DRD4DRD3
SCHEMBL31662946	0.73	PIM1 (0.41)	AKT1AKT2DRD2DRD4DRD3
SCHEMBL31662653	0.73	DRD2 (0.47)	AKT1AKT2DRD2DRD4DRD3
SCHEMBL31663111	0.73	DRD2 (0.45)	AKT1AKT2DRD2DRD4DRD3
SCHEMBL31662757	0.73	DRD2 (0.39)	DRD2DRD4DRD3TLR9TLR8
SCHEMBL31662847	0.71	DRD2 (0.44)	AKT1AKT2DRD2DRD4DRD3
SCHEMBL31663193	0.71	DRD2 (0.50)	AKT1AKT2DRD2DRD4DRD3
SCHEMBL31663408	0.70	DRD2 (0.46)	AKT1AKT2DRD2DRD4DRD3
SCHEMBL31663004	0.68	DRD2 (0.45)	AKT1AKT2DRD2DRD4DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2025149628-A1	PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE	ASTRAZENECA AB (SE)	2025-07-17	—	—	WO	claimed