Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.47 |
| ▸ | DRD4 | P21917 | 5/20 | 0.47 |
| ▸ | DRD3 | P35462 | 4/20 | 0.47 |
| ▸ | AKT1 | P31749 | 4/20 | 0.46 |
| ▸ | AKT2 | P31751 | 4/20 | 0.46 |
| ▸ | PIM1 | P11309 | 2/20 | 0.44 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31663134 | 1.00 | DRD2 (0.47) | DRD2DRD4DRD3AKT1AKT2 | |
| SCHEMBL31662653 | 0.89 | DRD2 (0.47) | DRD2DRD4DRD3AKT1AKT2 | |
| SCHEMBL31662946 | 0.87 | PIM1 (0.41) | DRD2DRD4DRD3AKT1AKT2 | |
| SCHEMBL31663004 | 0.85 | DRD2 (0.45) | DRD2DRD4DRD3AKT1AKT2 | |
| SCHEMBL31663408 | 0.83 | DRD2 (0.46) | DRD2DRD4DRD3AKT1AKT2 | |
| SCHEMBL31663329 | 0.83 | LRRK2 (0.46) | DRD2DRD4DRD3AKT1AKT2 | |
| SCHEMBL31663193 | 0.82 | DRD2 (0.50) | DRD2DRD4DRD3AKT1AKT2 | |
| SCHEMBL31663162 | 0.80 | PIM1 (0.42) | DRD2DRD4DRD3AKT1AKT2 | |
| SCHEMBL31662792 | 0.79 | DRD2 (0.47) | DRD2DRD4DRD3AKT1AKT2 | |
| SCHEMBL31663111 | 0.79 | DRD2 (0.45) | DRD2DRD4DRD3AKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |