Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | WNT1 | P04628 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31663134 | 0.87 | DRD2 (0.47) | PIM1DRD2DRD4DRD3AKT1 | |
| SCHEMBL31663092 | 0.87 | DRD2 (0.47) | PIM1DRD2DRD4DRD3AKT1 | |
| SCHEMBL31662653 | 0.76 | DRD2 (0.47) | DRD2DRD4DRD3AKT1AKT2 | |
| SCHEMBL8549897 | 0.74 | DRD2 (0.52) | PIM1DRD2DRD4DRD3AKT1 | |
| SCHEMBL31663004 | 0.73 | DRD2 (0.45) | PIM1DRD2DRD4DRD3AKT1 | |
| SCHEMBL31663162 | 0.73 | PIM1 (0.42) | PIM1DRD2DRD4DRD3AKT1 | |
| SCHEMBL31662758 | 0.73 | AKT1 (0.42) | PIM1DRD2DRD4DRD3AKT1 | |
| SCHEMBL31663408 | 0.71 | DRD2 (0.46) | DRD2DRD4DRD3AKT1AKT2 | |
| SCHEMBL27955820 | 0.70 | ALDH1A1 (0.54) | PIM1CYP11B2 | |
| SCHEMBL8547063 | 0.69 | DRD4 (0.57) | DRD2DRD4DRD3AKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |