Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.45 |
| ▸ | DRD4 | P21917 | 7/20 | 0.45 |
| ▸ | DRD3 | P35462 | 6/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31663193 | 0.82 | DRD2 (0.50) | DRD2DRD4DRD3SLC6A4ALDH1A1 | |
| SCHEMBL31662792 | 0.80 | DRD2 (0.47) | DRD2DRD4DRD3SLC6A4ALDH1A1 | |
| SCHEMBL31663004 | 0.79 | DRD2 (0.45) | DRD2DRD4DRD3ALDH1A1HPGD | |
| SCHEMBL31663111 | 0.78 | DRD2 (0.45) | DRD2DRD4DRD3SLC6A4ALDH1A1 | |
| SCHEMBL31662847 | 0.77 | DRD2 (0.44) | DRD2DRD4DRD3SLC6A4ALDH1A1 | |
| SCHEMBL31662653 | 0.76 | DRD2 (0.47) | DRD2DRD4DRD3ALDH1A1HPGD | |
| SCHEMBL31663134 | 0.76 | DRD2 (0.47) | DRD2DRD4DRD3AKT1AKT2 | |
| SCHEMBL31663092 | 0.76 | DRD2 (0.47) | DRD2DRD4DRD3AKT1AKT2 | |
| SCHEMBL31663408 | 0.75 | DRD2 (0.46) | DRD2DRD4DRD3SLC6A4ALDH1A1 | |
| SCHEMBL31663310 | 0.68 | MAPT (0.43) | DRD2DRD4DRD3ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | claimed |