Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662428 | 0.91 | DHODH (0.37) | CD38LRRK2MAPK1MAPK14CHRM1 | |
| SCHEMBL31661945 | 0.91 | LRRK2 (0.36) | CD38LRRK2SCN9AMAPK1MAPK14 | |
| SCHEMBL31662611 | 0.91 | PDE4B (0.36) | MAPK1PDE4BRORCOPRK1MAPT | |
| SCHEMBL31662165 | 0.90 | IRAK4 (0.37) | CD38LRRK2SCN9A | |
| SCHEMBL31662086 | 0.88 | LRRK2 (0.34) | CD38LRRK2SCN9AMAPK1PDE4B | |
| SCHEMBL31661929 | 0.86 | IRAK4 (0.37) | LRRK2SCN9A | |
| SCHEMBL31662279 | 0.85 | IRAK4 (0.37) | LRRK2SCN9AMAPK1CHRM1 | |
| SCHEMBL31662135 | 0.85 | IRAK4 (0.37) | LRRK2SCN9AMAPK1CHRM1 | |
| SCHEMBL31662162 | 0.85 | IRAK4 (0.37) | LRRK2SCN9AMAPK1CHRM1 | |
| SCHEMBL31662113 | 0.83 | SCN9A (0.39) | CD38SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |