Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.33 |
| ▸ | CD38 | P28907 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 2/20 | 0.31 |
| ▸ | CDK8 | P49336 | 2/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662770 | 0.88 | CD38 (0.36) | LRRK2SCN9ACD38MAPK1MAPK14 | |
| SCHEMBL31661945 | 0.88 | LRRK2 (0.36) | LRRK2SCN9ACD38HRH3MAPK1 | |
| SCHEMBL31662428 | 0.88 | DHODH (0.37) | LRRK2CD38HRH3MAPK1MAPK14 | |
| SCHEMBL31662165 | 0.87 | IRAK4 (0.37) | LRRK2SCN9ACD38 | |
| SCHEMBL31661929 | 0.83 | IRAK4 (0.37) | LRRK2SCN9AHRH3 | |
| SCHEMBL31662279 | 0.82 | IRAK4 (0.37) | LRRK2SCN9AMAPK1CHRM1 | |
| SCHEMBL31662135 | 0.82 | IRAK4 (0.37) | LRRK2SCN9AMAPK1CHRM1 | |
| SCHEMBL31662162 | 0.82 | IRAK4 (0.37) | LRRK2SCN9AMAPK1CHRM1 | |
| SCHEMBL31661957 | 0.82 | IRAK4 (0.36) | LRRK2SCN9ACD38MAPK1PDE4B | |
| SCHEMBL31662113 | 0.81 | SCN9A (0.39) | SCN9ACD38DRD4TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |