SCHEMBL31662831

SCHEMBL31662831

CN[C@@H](C)C(=O)N1CCN(c2ccc(CN3C(=O)C(Cl)=C(Cl)C3O)cc2OC)CC1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MC4R P32245 6/20 0.38
KMT2A Q03164 6/20 0.38
MEN1 O00255 5/20 0.38
KDM4E B2RXH2 3/20 0.38
MAPT P10636 3/20 0.38
NPC1 O15118 1/20 0.38
TACR1 P25103 1/20 0.38
MC5R P33032 2/20 0.37
MC3R P41968 2/20 0.37
NPSR1 Q6W5P4 2/20 0.36
LMNA P02545 2/20 0.36
ALDH1A1 P00352 3/20 0.36
TP53 P04637 1/20 0.36
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
DRD2 P14416 1/20 0.35
DRD4 P21917 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31662839 0.88 MC4R (0.37) MC4RKMT2AMAPTMC5RMC3R
SCHEMBL31662699 0.84 GAA (0.39) KMT2AMEN1KDM4EMAPTNPSR1
SCHEMBL31662870 0.83 P2RX7 (0.41) MAPTNPSR1LMNATP53DRD2
SCHEMBL31662796 0.80 AOC3 (0.39) KMT2AMEN1ALDH1A1
SCHEMBL31662904 0.78 MAPT (0.35) MC4RMAPTNPSR1LMNAALDH1A1
SCHEMBL31662853 0.76 MEN1 (0.42) KMT2AMEN1KDM4ENPSR1LMNA
SCHEMBL31663171 0.74 SMN1; SMN2 (0.41) KMT2AMEN1MAPTNPSR1LMNA
SCHEMBL31662829 0.71 VEGFA (0.41) KMT2AMEN1MAPTNPSR1LMNA
SCHEMBL31662883 0.71 GAA (0.38) MC4RKMT2AMEN1KDM4EMAPT
SCHEMBL31663031 0.69 GFER (0.47) KMT2AMEN1KDM4EMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025147756-A1 VIRAL SENSITIZERS COMPOSITIONS, METHODS AND USES THEREOF OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) 2025-07-17 WO disclosed