SCHEMBL31662699

SCHEMBL31662699

CN[C@@H](C)C(=O)N1CCN(c2ccc(CN3C(=O)C(Cl)=C(Cl)C3O)cc2)CC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.39
MAPT P10636 3/20 0.39
LMNA P02545 2/20 0.39
HTT P42858 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
KDM4E B2RXH2 2/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
ALOX12 P18054 1/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CCR1 P32246 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
NAMPT P43490 2/20 0.36
ME2 P23368 1/20 0.35
ME1 P48163 1/20 0.35
ME3 Q16798 1/20 0.35
NPSR1 Q6W5P4 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31662796 0.87 AOC3 (0.39) MEN1KMT2AME2ME1ME3
SCHEMBL31662904 0.87 MAPT (0.35) MAPTLMNAHTTSMN1; SMN2TSHR
SCHEMBL31662839 0.86 MC4R (0.37) MAPTLMNATSHRKMT2ANPSR1
SCHEMBL31662883 0.85 GAA (0.38) GAAMAPTLMNAHTTSMN1; SMN2
SCHEMBL31662831 0.84 MC4R (0.38) MAPTLMNAKDM4EMAPK1TDP1
SCHEMBL31663031 0.84 GFER (0.47) GAAMAPTLMNAHTTSMN1; SMN2
SCHEMBL31662690 0.80 ENPP2 (0.35) GAAMAPTLMNAHTTSMN1; SMN2
SCHEMBL31663040 0.80 ME2 (0.44) GAAMAPTLMNAMEN1KMT2A
SCHEMBL31662801 0.78 SMN1; SMN2 (0.53) MAPTLMNAHTTSMN1; SMN2TSHR
SCHEMBL31662775 0.76 ADRB1 (0.45) LMNAHTTKDM4ETSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025147756-A1 VIRAL SENSITIZERS COMPOSITIONS, METHODS AND USES THEREOF OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) 2025-07-17 WO disclosed