SCHEMBL31662829

SCHEMBL31662829

CC(C)(C)OC(=O)N1CCN(c2ccc(CN3C(=O)C(Cl)=C(Cl)C3O)cc2N)CC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VEGFA P15692 1/20 0.41
EGLN1 Q9GZT9 1/20 0.41
SMARCA2 P51531 1/20 0.41
SMARCA4 P51532 1/20 0.41
PBRM1 Q86U86 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
TP53 P04637 1/20 0.40
HTT P42858 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
KDM1A O60341 3/20 0.39
DDB1 Q16531 1/20 0.38
CRBN Q96SW2 1/20 0.38
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA4 P22748 1/20 0.37
CA5A P35218 1/20 0.37
CA7 P43166 1/20 0.37
CA5B Q9Y2D0 1/20 0.37
MEN1 O00255 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31662870 0.88 P2RX7 (0.41) VEGFAEGLN1SMN1; SMN2TP53HTT
SCHEMBL31662710 0.88 HSD17B10 (0.42) NPSR1MEN1KMT2ALMNAALDH1A1
SCHEMBL31663171 0.87 SMN1; SMN2 (0.41) VEGFAEGLN1SMN1; SMN2TP53HTT
SCHEMBL31662801 0.86 SMN1; SMN2 (0.53) VEGFAEGLN1SMN1; SMN2TP53HTT
SCHEMBL31662938 0.85 MC4R (0.34) LMNAPRMT1
SCHEMBL31662839 0.82 MC4R (0.37) NPSR1KMT2ALMNAMAPTALDH1A1
SCHEMBL31662817 0.81 GPR119 (0.50) VEGFAEGLN1SMN1; SMN2TP53DDB1
SCHEMBL31662803 0.80 HTR1A (0.35) HTTLMNAALDH1A1PRMT1
SCHEMBL31663029 0.79 CCR4 (0.38) KMT2A
SCHEMBL31662878 0.78 SMN1; SMN2 (0.42) VEGFAEGLN1SMN1; SMN2HTTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025147756-A1 VIRAL SENSITIZERS COMPOSITIONS, METHODS AND USES THEREOF OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) 2025-07-17 WO disclosed