Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.41 |
| ▸ | DRD3 | P35462 | 5/20 | 0.41 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31558703 | 0.74 | KDM4E (0.36) | DRD2DRD3DRD4GRM5 | |
| SCHEMBL26157120 | 0.71 | HTR6 (0.44) | DRD2DRD3HTR6SIGMAR1SETD7 | |
| SCHEMBL10635938 | 0.67 | HTR6 (0.39) | DRD2DRD3HTR6SIGMAR1SETD7 | |
| SCHEMBL31558715 | 0.67 | GRM5 (0.43) | DRD2DRD3DRD4GRM5 | |
| SCHEMBL31558712 | 0.67 | GRM5 (0.40) | DRD2DRD3DRD4GRM5 | |
| SCHEMBL5765159 | 0.66 | HTR6 (0.38) | DRD2DRD3HTR6SIGMAR1SETD7 | |
| SCHEMBL31558707 | 0.66 | GRM5 (0.42) | DRD2DRD3DRD4GRM5 | |
| SCHEMBL19604914 | 0.65 | ALDH1A1 (0.46) | HTR6SIGMAR1SETD7 | |
| SCHEMBL14601668 | 0.65 | SIGMAR1 (0.60) | SIGMAR1 | |
| SCHEMBL31558708 | 0.64 | GRM5 (0.42) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |