Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077864 | 0.71 | CYP2D6 (0.46) | CRHBPCRHR2CYP2D6ALDH1A1CYP2C19 | |
| SCHEMBL29212985 | 0.69 | CACNA2D1 (0.40) | CRHBPCRHR2CYP2D6ALDH1A1CYP2C19 | |
| SCHEMBL10981113 | 0.68 | TSHR (0.38) | CRHBPCRHR2CYP2D6ALDH1A1CYP2C19 | |
| SCHEMBL28606840 | 0.67 | ALDH1A1 (0.43) | ALDH1A1CYP2C19CYP1A2KMT2ATSHR | |
| SCHEMBL26105458 | 0.67 | ALDH1A1 (0.43) | ALDH1A1CYP2C19CYP1A2KMT2ATSHR | |
| SCHEMBL127044 | 0.67 | ALDH1A1 (0.43) | ALDH1A1CYP2C19CYP1A2KMT2ATSHR | |
| SCHEMBL16550589 | 0.66 | TSHR (0.43) | CRHBPCRHR2ALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL362964 | 0.66 | TSHR (0.43) | ALDH1A1CYP2C19CYP1A2KDM4EPABPC1 | |
| SCHEMBL18133808 | 0.66 | TSHR (0.43) | CRHBPCRHR2ALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL29211084 | 0.66 | TSHR (0.43) | CRHBPCRHR2ALDH1A1CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149498-A1 | BENZYLPIPERIDINE DERIVATIVES AS TRP4 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |