Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.38 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.38 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.38 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.38 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.38 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.38 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.38 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.38 |
| ▸ | LDLR | P01130 | 1/20 | 0.38 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 3/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31663072 | 0.79 | PDE4D (0.41) | DRD1PDE4DPOLBNPSR1 | |
| SCHEMBL28060611 | 0.78 | DRD1 (0.51) | DRD1POLBMEN1KMT2A | |
| SCHEMBL31662882 | 0.76 | DRD1 (0.40) | PDE3BPDE3ADRD1PDE4DCYP1A2 | |
| SCHEMBL31662950 | 0.73 | ALOX15 (0.50) | DRD1CYP1A2POLBMEN1KMT2A | |
| SCHEMBL31663217 | 0.73 | ALOX15 (0.50) | DRD1CYP1A2MEN1KMT2A | |
| SCHEMBL31662954 | 0.72 | MAPT (0.43) | HPGDSDRD1MEN1KMT2A | |
| SCHEMBL31662943 | 0.72 | PDE4D (0.38) | DRD1PDE4DPOLB | |
| SCHEMBL31662955 | 0.71 | SMN1; SMN2 (0.38) | PDE3BPDE3ADRD1PDE4DCYP1A2 | |
| SCHEMBL31662999 | 0.71 | GRIN2B (0.35) | PDE3BPDE3ADRD1PDE4DCYP1A2 | |
| SCHEMBL31663267 | 0.70 | KMT2A (0.43) | DRD1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149498-A1 | BENZYLPIPERIDINE DERIVATIVES AS TRP4 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |