Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 3/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31663004 | 0.83 | DRD2 (0.45) | DRD2DRD4DRD3KDM4EALDH1A1 | |
| SCHEMBL31663134 | 0.83 | DRD2 (0.47) | DRD2DRD4DRD3MAPTLMNA | |
| SCHEMBL31663092 | 0.83 | DRD2 (0.47) | DRD2DRD4DRD3MAPTLMNA | |
| SCHEMBL31663408 | 0.79 | DRD2 (0.46) | DRD2DRD4DRD3ALDH1A1HPGD | |
| SCHEMBL31662653 | 0.79 | DRD2 (0.47) | DRD2DRD4DRD3ALDH1A1HPGD | |
| SCHEMBL31663193 | 0.76 | DRD2 (0.50) | DRD2DRD4DRD3KDM4EALDH1A1 | |
| SCHEMBL31662792 | 0.74 | DRD2 (0.47) | DRD2DRD4DRD3KDM4EALDH1A1 | |
| SCHEMBL31663111 | 0.74 | DRD2 (0.45) | DRD2DRD4DRD3KDM4EALDH1A1 | |
| SCHEMBL31662847 | 0.72 | DRD2 (0.44) | DRD2DRD4DRD3KDM4EALDH1A1 | |
| SCHEMBL31662760 | 0.71 | DRD2 (0.45) | DRD2DRD4DRD3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |