SCHEMBL316631

SCHEMBL316631

Oc1cnc2cncnc2n1

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PIK3CG P48736 1/20 0.44
EGFR P00533 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31621377 0.83 PIK3CG (0.44) PIK3CGEGFR
SCHEMBL315449 0.83 PIK3CG (0.44) PIK3CGEGFR
SCHEMBL3292267 0.76 PIK3CG (0.47) PIK3CGEGFR
SCHEMBL29924424 0.74 PIK3CG (0.37) PIK3CGEGFR
SCHEMBL2467156 0.74 ALDH1A1 (0.41) PIK3CGEGFR
SCHEMBL30211632 0.74 PIK3CG (0.37) PIK3CGEGFR
SCHEMBL316630 0.74 PIK3CG (0.37) PIK3CGEGFR
SCHEMBL4389242 0.74 PIK3CG (0.37) PIK3CGEGFR
SCHEMBL2011723 0.74 PIK3CG (0.37) PIK3CGEGFR
SCHEMBL2011726 0.74 EGFR (0.38) PIK3CGEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5385990-A Blend of epoxy compound, amine hardener and hydroxy substituted aromatic compound LORD CORPORATION (US) 1995-01-31 US claimed
CN-1087367-A Structural adhesive composition with high temperature resistance LORD CORP (US) 1994-06-01 CN claimed
EP-0596622-A2 Epoxy resin structural adhesive composition having high temperature resistance LORD CORPORATION (US) 1994-05-11 EP claimed
US-4758312-A Adding colorless electrochemically active compound having positive reduction potential NALCO CHEMICAL COMPANY (US) 1988-07-19 US claimed
US-9918934-B2 Linker-based lecithin microemulsion delivery vehicles ACOSTA ZARA EDGAR JOEL (CA) 2018-03-20 US disclosed
EP-2120871-B2 LINKER-BASED LECITHIN MICROEMULSION DELIVERY VEHICLES ACOSTA-ZARA EDGAR JOEL (CA) 2017-12-20 EP disclosed
US-9115341-B2 Method for expanding hematopoietic stem cells using heterocyclic compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-08-25 US disclosed
EP-2120871-B1 LINKER-BASED LECITHIN MICROEMULSION DELIVERY VEHICLES ACOSTA-ZARA EDGAR JOEL (CA) 2014-11-26 EP disclosed
CN-101636148-B Linker-based lecithin microemulsion delivery vehicle ACOSTA-ZARA EDGAR JOEL 2014-02-26 CN disclosed
US-8440666-B2 Pyridazinone compounds and P2X7 receptor inhibitors NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-05-14 US disclosed
US-20120107273-A1 NEW PIPERAZINE COMPOUND AND USE THEREOF AS A HCV POLYMERASE INHIBITOR JAPAN TOBACCO INC. (JP) 2012-05-03 US disclosed
US-20120107273-A1 NEW PIPERAZINE COMPOUND AND USE THEREOF AS A HCV POLYMERASE INHIBITOR JAPAN TOBACCO INC. (JP) 2012-05-03 US disclosed
CN-1798739-A 3-alkylidenehydrazino substituted heteroaryl compounds as thrombopoietin receptor activators NISSAN CHEMICAL IND LTD (JP) 2006-07-05 CN disclosed
CN-1067096-C Structural adhesive composition having high temperature resistance LORD CORP (US) 2001-06-13 CN disclosed
US-5385990-A Blend of epoxy compound, amine hardener and hydroxy substituted aromatic compound LORD CORPORATION (US) 1995-01-31 US disclosed
CN-1087367-A Structural adhesive composition with high temperature resistance LORD CORP (US) 1994-06-01 CN disclosed
EP-0596622-A2 Epoxy resin structural adhesive composition having high temperature resistance LORD CORPORATION (US) 1994-05-11 EP disclosed
US-4758312-A Adding colorless electrochemically active compound having positive reduction potential NALCO CHEMICAL COMPANY (US) 1988-07-19 US disclosed
EP-0237738-A2 Method for in situ corrosion detection using electrochemically active compounds NALCO CHEMICAL COMPANY (US) 1987-09-23 EP disclosed
US-4683035-A Method for in situ corrosion detection using electrochemically active compounds NALCO CHEMICAL COMPANY (US) 1987-07-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120107273-A1 NEW PIPERAZINE COMPOUND AND USE THEREOF AS A HCV POLYMERASE INHIBITOR POLR1C, POLR2E, POLR2H PIK3CG 2052/4885EGFR 4646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.