Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.32 |
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.31 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662894 | 0.87 | SYK (0.32) | MAP3K12SYK | |
| SCHEMBL31663322 | 0.87 | STIM1 (0.35) | PIK3CACYP2C19DGAT1KCNH2MAP3K12 | |
| SCHEMBL31663003 | 0.84 | MET (0.35) | MAP3K12SYK | |
| SCHEMBL31663184 | 0.82 | PTGES (0.38) | SCN9AMAP3K12FLT3SYKAURKB | |
| SCHEMBL26849014 | 0.71 | KCNH2 (0.42) | PIK3CACYP2C19KCNH2CYP3A4CYP2C9 | |
| SCHEMBL25408338 | 0.70 | KCNH2 (0.46) | PIK3CACYP2C19KCNH2MAP3K12CYP3A4 | |
| SCHEMBL30567651 | 0.70 | KCNH2 (0.46) | PIK3CACYP2C19KCNH2MAP3K12CYP3A4 | |
| SCHEMBL31663278 | 0.66 | GRIN2B (0.37) | — | |
| SCHEMBL18003627 | 0.64 | PIK3CA (0.52) | PIK3CAKCNH2 | |
| SCHEMBL31662943 | 0.64 | PDE4D (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149498-A1 | BENZYLPIPERIDINE DERIVATIVES AS TRP4 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |