Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STIM1 | Q13586 | 1/20 | 0.35 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | ASIC1 | P78348 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.33 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31663301 | 0.87 | USP1 (0.34) | PIK3CACYP2C19FLT3SYKAURKB | |
| SCHEMBL31662894 | 0.74 | SYK (0.32) | SYKMAP3K12 | |
| SCHEMBL31663003 | 0.71 | MET (0.35) | SYKMAP3K12 | |
| SCHEMBL31663184 | 0.69 | PTGES (0.38) | FLT3SYKAURKBMAP3K12PDE10A | |
| SCHEMBL25406855 | 0.69 | KCNH2 (0.48) | PIK3CAKCNH2PTGS2PDE10APIK3CD | |
| SCHEMBL26849009 | 0.69 | SLC34A1 (0.43) | PIK3CAKCNH2PDE10APIK3CDPIK3CB | |
| SCHEMBL30567672 | 0.69 | KCNH2 (0.48) | PIK3CAKCNH2PTGS2PDE10APIK3CD | |
| SCHEMBL31662999 | 0.67 | GRIN2B (0.35) | CYP2C19KCNH2MAP3K12 | |
| SCHEMBL18003627 | 0.66 | PIK3CA (0.52) | PIK3CAKCNH2PDE10APIK3CDPIK3CB | |
| SCHEMBL16397962 | 0.66 | DGAT1 (0.41) | PIK3CASYKKCNH2DGAT1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149498-A1 | BENZYLPIPERIDINE DERIVATIVES AS TRP4 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |