Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2558075 | 0.81 | CHEK1 (0.43) | CYP11B2MEN1KMT2A | |
| SCHEMBL19703391 | 0.80 | GFER (0.49) | CYP11B2CASP6GFERTGFBR1ACVR1 | |
| SCHEMBL15646504 | 0.79 | CHRNB2 (0.45) | — | |
| SCHEMBL19279668 | 0.79 | ADAMTS5 (0.53) | CYP11B2CASP6GFERTGFBR1ACVR1 | |
| SCHEMBL2552859 | 0.78 | GFER (0.50) | CASP6GFERMEN1MAPTKMT2A | |
| SCHEMBL19703394 | 0.77 | CASP6 (0.49) | CYP11B2CASP6GFERTGFBR1ACVR1 | |
| SCHEMBL21273927 | 0.76 | GFER (0.65) | CASP6GFERMEN1MAPTKMT2A | |
| SCHEMBL29957858 | 0.75 | LRRK2 (0.43) | CYP11B2MAPTPIK3CD | |
| SCHEMBL13671979 | 0.75 | LRRK2 (0.43) | CYP11B2MAPTPIK3CD | |
| SCHEMBL15206038 | 0.74 | CHRNB2 (0.55) | CYP11B2CASP6GFERTGFBR1ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |