Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803148 | 0.88 | L3MBTL1 (0.48) | TSHRL3MBTL1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL5900467 | 0.82 | L3MBTL1 (0.44) | TSHRL3MBTL1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL7429605 | 0.81 | L3MBTL1 (0.43) | TSHRL3MBTL1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL1748473 | 0.78 | MAPK1 (0.46) | TSHRL3MBTL1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL27834208 | 0.77 | L3MBTL1 (0.52) | TSHRL3MBTL1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL27834209 | 0.76 | L3MBTL1 (0.55) | TSHRL3MBTL1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL22587293 | 0.76 | POLB (0.50) | TSHRL3MBTL1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL29319985 | 0.74 | ALDH1A1 (0.34) | TSHRL3MBTL1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL4980998 | 0.74 | ALDH1A1 (0.39) | KDM4EALDH1A1HPGDGAA | |
| SCHEMBL31663230 | 0.73 | L3MBTL1 (0.49) | TSHRL3MBTL1KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |